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Registros recuperados: 8
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Blood flow measurements in rats using four color microspheres during blockade of different vasopressor systems BJMBR
De Angelis,K.; Gama,V.M.; Farah,V.A.M.; Irigoyen,M.C..
The use of colored microspheres to adequately evaluate blood flow changes under different circumstances in the same rat has been validated with a maximum of three different colors due to methodological limitations. The aim of the present study was to validate the use of four different colors measuring four repeated blood flow changes in the same rat to assess the role of vasopressor systems in controlling arterial pressure (AP). Red (150,000), white (200,000), yellow (150,000), and blue (200,000) colored microspheres were infused into the left ventricle of 6 male Wistar rats 1) at rest and 2) after vasopressin (aAVP, 10 µg/kg, iv), 3) renin-angiotensin (losartan, 10 mg/kg, iv), and 4) sympathetic system blockade (hexamethonium, 20 mg/kg, iv) to determine...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Colored microspheres; Arterial pressure; Sympathetic system; Renin-angiotensin; Vasopressin; Local blood flow measurement.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000100018
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Cardiovascular control in experimental diabetes BJMBR
De Angelis,K.; Schaan,B.D.; Maeda,C.Y.; Dall'Ago,P.; Wichi,R.B.; Irigoyen,M.C..
Several studies have reported impairment in cardiovascular function and control in diabetes. The studies cited in this review were carried out from a few days up to 3 months after streptozotocin administration and were concerned with the control of the circulation. We observed that early changes (5 days) in blood pressure control by different peripheral receptors were maintained for several months. Moreover, the impairment of reflex responses observed after baroreceptor and chemoreceptor stimulation was probably related to changes in the efferent limb of the reflex arc (sympathetic and parasympathetic), but changes also in the central nervous system could not be excluded. Changes in renal sympathetic nerve activity during volume expansion were blunted in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Experimental diabetes; Arterial pressure; Autonomic control; Baroreflex; Chemoreflex; Cardiopulmonary reflex; Exercise training.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000900010
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Dynamic resistance training decreases sympathetic tone in hypertensive ovariectomized rats BJMBR
Shimojo,G.L.; Palma,R.K.; Brito,J.O.; Sanches,I.C.; Irigoyen,M.C.; De Angelis,K..
The aim of this study was to investigate the effects of resistance exercise training on hemodynamics and cardiac autonomic control in ovariectomized spontaneously hypertensive rats. Female rats were divided into 4 groups: sedentary control (SC), sedentary hypertensive (SH), sedentary hypertensive ovariectomized (SHO), and resistance-trained hypertensive ovariectomized (RTHO). Resistance exercise training was performed on a vertical ladder (5 days/week, 8 weeks) at 40-60% maximal load. Direct arterial pressure was recorded. Vagal and sympathetic tones were measured by heart rate (HR) responses to methylatropine (3 mg/kg, iv) and propranolol (4 mg/kg, iv). Ovariectomy resulted in additional increases in blood pressure in hypertensive rats and was associated...
Tipo: Info:eu-repo/semantics/report Palavras-chave: Resistance exercise training; Menopause; Hypertension; Sympathetic tone; Blood pressure.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000600523
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Exercise training prevents increased intraocular pressure and sympathetic vascular modulation in an experimental model of metabolic syndrome BJMBR
Castro,E.F.S.; Mostarda,C.T.; Rodrigues,B.; Moraes-Silva,I.C.; Feriani,D.J.; De Angelis,K.; Irigoyen,M.C..
The present study aimed to study the effects of exercise training (ET) performed by rats on a 10-week high-fructose diet on metabolic, hemodynamic, and autonomic changes, as well as intraocular pressure (IOP). Male Wistar rats receiving fructose overload in drinking water (100 g/L) were concomitantly trained on a treadmill for 10 weeks (FT group) or kept sedentary (F group), and a control group (C) was kept in normal laboratory conditions. The metabolic evaluation comprised the Lee index, glycemia, and insulin tolerance test (KITT). Arterial pressure (AP) was measured directly, and systolic AP variability was performed to determine peripheral autonomic modulation. ET attenuated impaired metabolic parameters, AP, IOP, and ocular perfusion pressure (OPP)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fructose; Exercise training; Intraocular pressure; Autonomic modulation.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000400332
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Familial history of hypertension-induced impairment on heart rate variability was not observed in strength-trained subjects BJMBR
Santa-Rosa,F.A.; Shimojo,G.L.; Sartori,M.; Rocha,A.C.; Francica,J.V.; Paiva,J.; Irigoyen,M.C.; De Angelis,K..
Family history of hypertension is an important predictive factor for hypertension and is associated with hemodynamic and autonomic abnormalities. Previous studies reported that strength training might reduce arterial blood pressure (AP), as well as improve heart rate variability (HRV). However, the benefits of strength training in the offspring of hypertensive parents have not been fully evaluated. Here, we analyzed the impact of strength training on hemodynamics and autonomic parameters in offspring of hypertensive subjects. We performed a cross-sectional study with sedentary or physically active offspring of normotensives (S-ON and A-ON) or hypertensives (S-OH and A-OH). We recorded RR interval for analysis of HRV. AP was similar between groups....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Family history; Arterial blood pressure; Cardiac autonomic modulation; Sympathetic modulation; Strength training.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200605
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Parasympathetic dysfunction is associated with insulin resistance in fructose-fed female rats BJMBR
Brito,J.O.; Ponciano,K.; Figueroa,D.; Bernardes,N.; Sanches,Í.C.; Irigoyen,M.C.; De Angelis,K..
The objective of the present study was to identify metabolic, cardiovascular and autonomic changes induced by fructose overload administered in the drinking water of rats for 8 weeks. Female Wistar rats (200-220 g) were divided into 2 groups: control (N = 8) and fructose-fed rats (N = 5; 100 mg/L fructose in drinking water for 8 weeks). The autonomic control of heart rate was evaluated by pharmacological blockade using atropine (3 mg/kg) and propranolol (4 mg/kg). The animals were submitted to an intravenous insulin tolerance test (ITT) and to blood glucose measurement. The fructose overload induced a significant increase in body weight (~10%) and in fasting glycemia (~28%). The rate constant of glucose disappearance (KITT) during ITT was lower in...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Female rats; Fructose; Blood pressure; Insulin resistance; Parasympathetic nervous system.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000900010
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Pleiotropic effects of simvastatin in physically trained ovariectomized rats BJMBR
Bernardes,N.; Brito,J.O.; Fernandes,T.G.; Llesuy,S.F.; Irigoyen,M.C.; Belló-Klein,A.; De Angelis,K..
This study tested the hypothesis that simvastatin treatment can improve cardiovascular and autonomic functions and membrane lipoperoxidation, with an increased effect when applied to physically trained ovariectomized rats. Ovariectomized rats were divided into sedentary, sedentary+simvastatin and trained+simvastatin groups (n = 8 each). Exercise training was performed on a treadmill for 8 weeks and simvastatin (5 mg/kg) was administered in the last 2 weeks. Blood pressure (BP) was recorded in conscious animals. Baroreflex sensitivity was evaluated by the tachycardic and bradycardic responses to BP changes. Cardiac vagal and sympathetic effects were determined using methylatropine and propranolol. Oxidative stress was evaluated based on heart and liver...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Menopause; Exercise training; Simvastatin; Autonomic function; Oxidative stress.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500447
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Tonic and reflex cardiovascular autonomic control in trained-female rats BJMBR
Sanches,I.C.; Sartori,M.; Jorge,L.; Irigoyen,M.C.; De Angelis,K..
The effects of exercise training on cardiovascular and autonomic functions were investigated in female rats. After an aerobic exercise training period (treadmill: 5 days/week for 8 weeks), conscious female Wistar (2 to 3 months) sedentary (S, N = 7) or trained rats (T, N = 7) were cannulated for direct arterial pressure (AP) recording in the non-ovulatory phases. Vagal (VT) and sympathetic tonus (ST) were evaluated by vagal (atropine) and sympathetic (propranolol) blockade. Baroreflex sensitivity was evaluated by the heart rate responses induced by AP changes. Cardiopulmonary reflex was measured by the bradycardic and hypotensive responses to serotonin. Resting bradycardia was observed in T (332 ± 7 bpm) compared with S animals (357 ± 10 bpm), whereas AP...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex; Cardiopulmonary reflex; Exercise training; Female; Heart rate.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000011
Registros recuperados: 8
Primeira ... 1 ... Última
 

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